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Everything you need to know about Saxenda
Everything you need to know about Saxenda

This article provides a detailed overview of Saxenda.

Updated over a month ago

General Inquiries

Saxenda is a GLP-1 receptor agonist that mimics a natural hormone in the body to regulate appetite and caloric intake. It is FDA-approved for chronic weight management in adults with obesity or overweight conditions who also have weight-related health issues, such as high blood pressure or diabetes. Saxenda helps reduce hunger, slow digestion, and increase feelings of fullness, which contributes to weight loss. Clinical trials have demonstrated its efficacy in achieving and maintaining significant weight loss when combined with a reduced-calorie diet and increased physical activity. While Saxenda is safe for most users, it is essential to consult with your medical team to ensure it is appropriate for your individual health needs.


Administration and Usage

Saxenda is administered as a daily injection using a prefilled pen. It is injected subcutaneously into the abdomen, thigh, or upper arm, and the injection site should be rotated to avoid irritation. The medication is started at a low dose and gradually increased over several weeks to minimize side effects, such as nausea. It is beneficial to inject Saxenda around the same time, for example, in the morning before breakfast. This helps maintain a stable blood sugar level. If you forget to inject your medication, do it as soon as possible. However, if it is almost time for the next dose, skip the missed dose.

There are no strict dietary restrictions while using Saxenda, but following a balanced, calorie-controlled diet can enhance its benefits. Moderate alcohol consumption is generally safe, but it’s wise to avoid excessive drinking. Saxenda is often used long-term for weight management, but some may discontinue after reaching their target weight, provided sustainable lifestyle changes are maintained. Always consult your medical team before stopping Saxenda, as they may recommend a tapering process.

Dosage

Each week, the dose of Saxenda should be increased, starting with 0.6 mg. Following this schedule consistently helps the body adapt to the medication. Monitoring how side effects present after each dose increase is crucial:

  • If side effects are minimal: Proceed to increase the dose as planned for the next week.

  • If side effects are strong: It may be best to maintain the same dosage and observe for stabilization before any further increase.

Stabilizing the condition before adjusting the dose ensures safety and effectiveness. If maintaining the dose due to side effects seems necessary, please contact us for further guidance to determine the best course of action.


Effectiveness

Saxenda has been shown to help individuals lose and maintain up to 15% of their body weight, with some achieving even greater results. Noticeable weight loss typically occurs within the first 4–8 weeks of use. If progress slows or stops, your nurse may evaluate your dosage, diet, or exercise routine to maximize results. Sustaining weight loss after discontinuing Saxenda requires ongoing lifestyle changes, as appetite and eating behaviors may revert to baseline levels. Beyond weight loss, Saxenda may improve weight-related health conditions, such as high blood pressure, cholesterol, and blood sugar control.


Safety and Side Effects

Saxenda is generally well-tolerated, but some users may experience side effects, especially during the initial weeks of use. Common side effects include nausea, vomiting, diarrhea, and constipation, which typically improve over time. Seek medical attention immediately if you experience severe symptoms or allergic reactions. Saxenda is approved for long-term use when monitored by a healthcare provider. However, it is not recommended during pregnancy or breastfeeding, as its safety in these situations has not been established. Always consult your doctor about any side effects or concerns regarding Saxenda.


Eligibility

Saxenda is approved for adults with a BMI of 30 or higher, or a BMI of 27 or higher with weight-related health conditions such as hypertension or type 2 diabetes. It is not typically prescribed for individuals without a medical need for weight loss. People with certain medical conditions, such as a history of pancreatitis, thyroid cancer, or severe kidney or liver disease, may not be eligible for Saxenda. It is approved for use in adults aged 18 and older and is often a good option even if other weight-loss medications have not been effective.


Lifestyle Considerations

Saxenda requires combining it with healthy habits because it will maximize its benefits. A balanced diet and regular exercise are highly recommended to enhance weight loss and improve overall health. Alcohol can be consumed in moderation, but excessive drinking may interfere with your progress. Saxenda reduces appetite, helping you feel fuller with smaller meals, but it does not eliminate hunger completely, enabling mindful eating choices. Most users report no significant changes in energy levels or mood, though establishing healthier routines may positively impact how you feel overall.


Technical and Storage Questions

Proper storage is crucial for preserving Saxenda’s effectiveness. Unopened pens should be refrigerated at temperatures between 2°C and 8°C. Once in use, pens can be stored at room temperature (up to 25°C) or in the refrigerator, but they must be used within 6 weeks. If a pen is left out of the fridge temporarily, it remains safe to use as long as it wasn’t exposed to high heat. If your injection pen malfunctions, contact the manufacturer or your pharmacy for assistance and a possible replacement.


This guide provides a comprehensive overview of what to expect when using Saxenda, addressing common questions and concerns. Always consult your medical team for personalized advice to ensure Saxenda is safe and effective for your weight management journey.

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